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allostery
A phenomenon whereby the conformation of an enzyme or other protein is altered by combination, at a site other than the substrate-binding site, with a small molecule, referred to as an effector, which results in either increased or decreased activity by the enzyme.
Source:
PAC, 1994, 66, 2587 (Glossary of bioanalytical nomenclature - Part 1: General terminology, body fluids, enzymology, immunology (IUPAC Recommendations 1994)) on page 2593
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Cite as:
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A.Wilkinson. Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic, J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. doi:10.1351/goldbook.
Last update: 2008-10-07; version: 2.0.2.
DOI of this term: doi:10.1351/goldbook.A00241.
Original PDF version (may be out of date): http://www.iupac.org/goldbook/A00241.pdf.
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