IUPAC > Gold Book > alphabetical index > B > bioavailabilty in pharmacokinetics
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bioavailability (general)biocatalyst
bioavailabilty
in pharmacokinetics
Ratio of the systemic exposure from extravascular (ev) exposure to that following intravenous (iv) exposure as described by the equation:
Math - e
where Math - ei is the bioavailabilty, Math - ei and Math - ei are areas under the (plasma) concentration-time curve following extravascular and intravenous administration, respectively, and Math - ei and Math - ei are the administered extravascular and intravenous doses.
Source:
PAC, 2004, 76, 1033 (Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)) on page 1041
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Cite as: IUPAC Compendium of Chemical Terminology, Electronic version, http://goldbook.iupac.org/BT06813.html.
Transformed and rewritten from PDF version (entry http://www.iupac.org/goldbook/BT06813.pdf)
by: Miloslav Nic, Jiri Jirat, Bedrich Kosata, ICT Prague, Czech Republic
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