A small molecule which increases (activator) or decreases (inhibitor) the activity of an (allosteric) protein by binding to the protein at the regulatory site (which is different from the substrate-binding catalytic site).
Source:
PAC, 1992, 64, 143
(Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992))
on page 152
Transformed and rewritten from PDF version (entry
http://www.iupac.org/goldbook/E01901.pdf)
by: Miloslav Nic, Jiri Jirat, Bedrich Kosata, ICT Prague, Czech Republic