Chromatography in which separation is based mainly on exclusion effects, such as differences in molecular size and/or shape or in charge. The term size-exclusion
chromatography may also be used when separation is based on molecular size. The terms
gel filtration and
gel-
permeation chromatography (
GPC) were used earlier to describe this process when the stationary phase is a swollen
gel. The term ion-exclusion
chromatography is specifically used for the separation of ions in an aqueous phase.
Source:
PAC, 1993, 65, 819
(Nomenclature for chromatography (IUPAC Recommendations 1993))
on page 826