A point
mutation involving either the deletion or
insertion of a
nucleotide in a
gene. By the frame-shift
mutation, the normal
reading frame used when decoding the nucleotide triplets in the gene is altered to another
reading frame.
Source:
PAC, 1992, 64, 143
(Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992))
on page 154