IUPAC > Gold Book > alphabetical index > F > first-pass effect
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first-order phase transitionFischer projection (Fischer–Tollens projection)
first-pass effect
Biotransformation and, in some cases, elimination of a substance in the liver after absorption from the intestine and before it reaches the systemic circulation.
Source:
PAC, 2004, 76, 1033 (Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)) on page 1052
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Cite as: IUPAC Compendium of Chemical Terminology, Electronic version, http://goldbook.iupac.org/FT06824.html.
Transformed and rewritten from PDF version (entry http://www.iupac.org/goldbook/FT06824.pdf)
by: Miloslav Nic, Jiri Jirat, Bedrich Kosata, ICT Prague, Czech Republic
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