IUPAC > Gold Book > alphabetical index > I > immobilization in biotechnology



in biotechnology
The technique used for the physical or chemical fixation of cells, organelles, enzymes, or other proteins (e.g. monoclonal antibodies ) onto a solid support, into a solid matrix or retained by a membrane, in order to increase their stability and make possible their repeated or continued use. The principle is also used for affinity chromatography.
PAC, 1992, 64, 143 (Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)) on page 157
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IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic, J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. doi:10.1351/goldbook.
Last update: 2014-02-24; version: 2.3.3.
DOI of this term: doi:10.1351/goldbook.I02973.
Original PDF version: http://www.iupac.org/goldbook/I02973.pdf. The PDF version is out of date and is provided for reference purposes only. For some entries, the PDF version may be unavailable.
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