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limit of detection
in analysis
The limit of detection, expressed as the concentration, Math - symbol, or the quantity, Math - symbol, is derived from the smallest measure, Math - symbol, that can be detected with reasonable certainty for a given analytical procedure. The value of Math - symbol is given by the equation
Math - e
where Math - text is the mean of the blank measures, Math - symbol is the standard deviation of the blank measures, and Math - symbol is a numerical factor chosen according to the confidence level desired.
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Cite as:
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A.Wilkinson. Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic, J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. doi:10.1351/goldbook.
DOI of this term: doi:10.1351/goldbook.L03540
Original PDF version (may be out of date): http://www.iupac.org/goldbook/L03540.pdf.
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