IUPAC > Gold Book > alphabetical index > L > logit



In competitive binding assays, the logit-log dose relationship, in which the response is defined by: R = logit y = log 10 ( y 1 − y ) where y = b b 0 with b = fraction of tracer bound and b 0 = value of b with no unlabelled ligand in the system. Logit transformed assay data frequently yield straight-line dose-response curves, amenable to statistical analysis.
PAC, 1994, 66, 2513 (Nomenclature for radioanalytical chemistry (IUPAC Recommendations 1994)) on page 2522
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IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic, J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. doi:10.1351/goldbook.
Last update: 2014-02-24; version: 2.3.3.
DOI of this term: doi:10.1351/goldbook.L03613.
Original PDF version: http://www.iupac.org/goldbook/L03613.pdf. The PDF version is out of date and is provided for reference purposes only. For some entries, the PDF version may be unavailable.
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