IUPAC > Gold Book > alphabetical index > L > lowest observed adverse effect level (LOAEL)
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lowest-observed-adverse-effect-level (LOAEL)lowest-observed-effect-level (LOEL)
lowest observed adverse effect level (LOAEL)
Lowest concentration or amount of a substance, found by experiment or observation, which causes an adverse alteration of morphology, functional capacity, growth, development, or life span of a target organism distinguishable from normal (control) organisms of the same species and strain under defined conditions of exposure.
Source:
PAC, 1993, 65, 2003 (Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993)) on page 2065
PAC, 2001, 73, 1023
This definition replaces an earlier definition of lowest-observed-adverse-effect-level (LOAEL).
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Cite as: IUPAC Compendium of Chemical Terminology, Electronic version, http://goldbook.iupac.org/LT06909.html.
Transformed and rewritten from PDF version (entry http://www.iupac.org/goldbook/LT06909.pdf)
by: Miloslav Nic, Jiri Jirat, Bedrich Kosata, ICT Prague, Czech Republic
Version for print | History of this term
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