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no observed adverse effect level (NOAEL)

Greatest concentration or amount found by experiment or observation, which causes no detectable adverse alteration of morphology, functional capacity, growth, development, or life span of the target organism under defined conditions.
Source:
PAC, 1993, 65, 2003 (Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993)) on page 2076
PAC, 2001, 73, 993 (Risk assessment for occupational exposure to chemicals. A review of current methodology (IUPAC Technical Report)) on page 1023
This definition replaces an earlier definition of no-observed-adverse-effect-level (NOAEL).
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Cite as:
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic, J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. doi:10.1351/goldbook.
Last update: 2014-02-24; version: 2.3.3.
DOI of this term: doi:10.1351/goldbook.NT06911.
Original PDF version: http://www.iupac.org/goldbook/NT06911.pdf. The PDF version is out of date and is provided for reference purposes only. For some entries, the PDF version may be unavailable.
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