IUPAC > Gold Book > alphabetical index > P > phase I reaction of biotransformation
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phase I reaction
of biotransformation
Enzymic modification of a substance by oxidation, reduction, hydrolysis, hydration, dehydrochlorination, or other reactions catalyzed by enzymes of the cytosol, of the endoplasmic reticulum (microsomal enzymes) or of other cell organelles.
Source:
PAC, 2004, 76, 1033 (Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)) on page 1064
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Cite as: IUPAC Compendium of Chemical Terminology, Electronic version, http://goldbook.iupac.org/PT06836.html.
Transformed and rewritten from PDF version (entry http://www.iupac.org/goldbook/PT06836.pdf)
by: Miloslav Nic, Jiri Jirat, Bedrich Kosata, ICT Prague, Czech Republic
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