IUPAC > Gold Book > alphabetical index > P > phase II reaction of biotransformation
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phase I reaction of biotransformationphase inversion
phase II reaction
of biotransformation
Binding of a substance, or its metabolites from a phase I reaction, with endogenous molecules (conjugation), making more water-soluble derivatives that may be excreted in the urine or bile.
Source:
PAC, 2004, 76, 1033 (Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)) on page 1064
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Cite as: IUPAC Compendium of Chemical Terminology, Electronic version, http://goldbook.iupac.org/PT06837.html.
Transformed and rewritten from PDF version (entry http://www.iupac.org/goldbook/PT06837.pdf)
by: Miloslav Nic, Jiri Jirat, Bedrich Kosata, ICT Prague, Czech Republic
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