Endonucleases which recognize specific base sequences within a DNAhelix, creating a double-strand break of DNA. Type I restriction enzymes bind to these recognition sites but subsequently cut the DNA at different sites. Type II restriction enzymes both bind and cut within their recognition or target sites.
Source:
PAC, 1992, 64, 143
(Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992))
on page 164
Transformed and rewritten from PDF version (entry
http://www.iupac.org/goldbook/R05350.pdf)
by: Miloslav Nic, Jiri Jirat, Bedrich Kosata, ICT Prague, Czech Republic
