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toxicity

  1. Capacity to cause injury to a living organism defined with reference to the quantity of substance administered or absorbed, the way in which the substance is administered (inhalation, ingestion, topical application, injection) and distributed in time (single or repeated doses), the type and severity of injury, the time needed to produce the injury, the nature of the organism(s) affected and other relevant conditions.
  2. Adverse effects of a substance on a living organism defined with reference to the quantity of substance administered or absorbed, the way in which the substance is administered (inhalation, ingestion, topical application, injection) and distributed in time (single or repeated doses), the type and severity of injury, the time needed to produce the injury, the nature of the organism(s) affected, and other relevant conditions
  3. Measure of incompatibility of a substance with life: this quantity may be expressed as the reciprocal of the absolute value of median lethal dose (1 LD 50) or concentration (1 LC 50).
Source:
PAC, 1993, 65, 2003 (Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993)) on page 2107
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Cite as:
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic, J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. doi:10.1351/goldbook.
Last update: 2014-02-24; version: 2.3.3.
DOI of this term: doi:10.1351/goldbook.T06414.
Original PDF version: http://www.iupac.org/goldbook/T06414.pdf. The PDF version is out of date and is provided for reference purposes only. For some entries, the PDF version may be unavailable.
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