A phenomenon whereby the conformation
of an enzyme
or other protein is altered by combination, at a site other than the substrate-binding site
, with a small molecule, referred to as an effector
, which results in either increased or decreased activity by the enzyme.
PAC, 1994, 66, 2587
(Glossary of bioanalytical nomenclature - Part 1: General terminology, body fluids,
enzymology, immunology (IUPAC Recommendations 1994))
on page 2593
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A.Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. https://doi.org/10.1351/goldbook