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IUPAC > Gold Book > alphabetical index > A > antagonist
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  1. Substance that reverses or reduces the effect induced by an agonist.
  2. Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances.
See also: agonist
Source:
PAC, 1993, 65, 2003 (Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993)) on page 2014
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IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A.Wilkinson. Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic, J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. https://doi.org/10.1351/goldbook.
Last update: 2008-10-07; version: 2.0.2.
DOI of this term: https://doi.org/10.1351/goldbook.A00376.
Original PDF version (may be out of date): http://www.iupac.org/goldbook/A00376.pdf.
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