A parameter that can be used to identify a toxic effect in an individual
organism and can be used in extrapolation between species, or as an
indicator signalling an event or condition in a biological system or
sample and giving a measure of exposure, effect, or susceptibility.
The term 'biomarker
' is generally used in scientific publications. In
occupational hygiene and health, 'biological monitoring
'biological effect monitoring
' are used with the meaning 'monitoring
PAC, 2001, 73, 993
(Risk assessment for occupational exposure to chemicals. A review of current methodology
(IUPAC Technical Report))
on page 1022
PAC, 2004, 76, 1033
(Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003))
on page 1042
This definition replaces an earlier definition of biomarker.
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. https://doi.org/10.1351/goldbook