This term is used to express the extra-column volume
. Strictly speaking, the term 'dead-volume
' refers to volumes within the chromatographic system which are not swept by the mobile
phase. On the other hand, mobile phase is flowing through most of the extra-column
volumes. Due to this ambiguity the use of term 'dead-volume
' is discouraged.
PAC, 1993, 65, 819
(Nomenclature for chromatography (IUPAC Recommendations 1993))
on page 833
See also: Orange Book, p. 101
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. https://doi.org/10.1351/goldbook