A measure of the capability of a solute for hydrophobiclipophilic
interaction based on the partition coefficient
for distribution of the solute between octan-1-ol and water. The most general way
in correlation analysis
, etc. is as log
, but the behaviour of substituted benzene derivatives may be quantified by a substituent
, which is defined in a way analogous to the Hammett σ scale. There are various scales,
depending on the substrate series used as reference.
PAC, 1994, 66, 1077
(Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994))
on page 1119
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A.Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. https://doi.org/10.1351/goldbook