Endonucleases which recognize specific base sequences within a DNAhelix
, creating a double-strand break of DNA
. Type I restriction enzymes
bind to these recognition sites
but subsequently cut the DNA
at different sites. Type II restriction enzymes
both bind and cut within their recognition or target sites.
PAC, 1992, 64, 143
(Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992))
on page 164
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. https://doi.org/10.1351/goldbook