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two-dimensional chromatography

A procedure in which parts or all of the separated sample components are subjected to additional separation steps. This can be done e.g. by conducting a particular fraction eluting from the column into another column (system) having different separation characteristics. When combined with additional steps, this may be described as multi-dimensional chromatography. In planar chromatography two-dimensional chromatography refers to the chromatographic process in which the components are caused to migrate first in one direction and subsequently in a direction at right angles to the first one; the two elutions are carried out with different eluents.
PAC, 1993, 65, 819 (Nomenclature for chromatography (IUPAC Recommendations 1993)) on page 827
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IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: (2006-) created by M. Nic, J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8.
Last update: 2014-02-24; version: 2.3.3.
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