antagonism

https://doi.org/10.1351/goldbook.A00375
Combined effect of two or more factors which is smaller than the solitary effect of any one of those factors. In bioassays, the term may be used when a specified response is produced by exposure to either of two factors but not by exposure to both together.
See also:
synergism (in toxicology)
Source:
PAC, 1993, 65, 2003. (Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993)) on page 2014 [Terms] [Paper]