Process of the uptake
of potentially toxic substances by the body, the biotransformation
they undergo, the distribution of the substances and their metabolites in the tissues,
and the elimination
of the substances and their metabolites from the body. Both the amounts and the concentrations
of the substances and their metabolites are studied. The term has essentially the
same meaning as pharmacokinetics
, but the latter term should be restricted to the study of pharmaceutical substances.
PAC, 1993, 65, 2003
(Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993))
on page 2108
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8. https://doi.org/10.1351/goldbook