frame-shift mutation
A point mutation involving either the deletion or insertion of a nucleotide in a gene. By the frame-shift mutation, the normal reading frame used when decoding the nucleotide triplets in the gene is altered to another reading frame.
PAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 154 (