A phenomenon whereby the @C01258@ of an @E02159@ or other protein is altered by combination, at a site other than the substrate-@B00649@, with a small molecule, referred to as an @E01901@, which results in either increased or decreased activity by the enzyme.
PAC, 1994, 66, 2587. (Glossary of bioanalytical nomenclature - Part 1: General terminology, body fluids, enzymology, immunology (IUPAC Recommendations 1994)) on page 2593 [Terms] [Paper]