Lacking all symmetry elements (other than the trivial one of a one-fold axis of symmetry), i.e. belonging to the symmetry @P04703@ \(C_{1}\). The term has been used loosely (and incorrectly) to describe the absence of a rotation–reflection axis (alternating axis) in a molecule, i.e. as meaning @C01057@, and this usage persists in the traditional terms @A00479@, @A00484@, @A00483@, etc.
Blue Book, p. 480 [Terms] [Book]
PAC, 1996, 68, 2193. (Basic terminology of stereochemistry (IUPAC Recommendations 1996)) on page 2199 [Terms] [Paper]