Interaction between the @[email protected] binding sites of an @[email protected] Binding of a substrate molecule to one @[email protected] changes the affinity of the binding sites on the other subunits (cf. @[email protected]) to the substrate by induction of a @[email protected] change at the other binding sites. Cooperative @[email protected] typically display a sigmoid (S-shaped) plot of the reaction rate against substrate concentration.
PAC, 1992, 64, 143. (Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)) on page 151 [Terms] [Paper]