Member of a superfamily of heme-containing monooxygenases involved in @XT06755@ @M03858@, cholesterol @B00665@, and steroidogenesis, in eukaryotic organisms found mainly in the endoplasmic reticulum and inner mitochondrial @MT06878@ of cells. ‘P450’ refers to a feature in the carbon monoxide absorption difference spectrum at \(450\ \text{nm}\) caused by the presence of a thiolate in the axial position of the heme opposite to the carbon monoxide ligand.
PAC, 2004, 76, 1033. (Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)) on page 1048 [Terms] [Paper]