## clearance

in toxicology
https://doi.org/10.1351/goldbook.CT06860
1. Volume of blood or plasma or mass of an organ effectively cleared of a substance by @[email protected] (@[email protected] and excretion) divided by time of @[email protected]
Note:
Total @[email protected] is the sum of the clearances of each eliminating organ or tissue for a given substance.
2. (in pulmonary toxicology) Volume or mass of lung cleared divided by time of @[email protected]; used qualitatively to describe removal of any inhaled substance which deposits on the lining surface of the lung.
3. (in renal toxicology) Quantification of the removal of a substance by the kidneys by the processes of @[email protected] and secretion; @[email protected] is calculated by relating the rate of renal excretion to the plasma concentration.
See also:
clearance, $$^{\Delta V}/_{\Delta t}$$
Source:
PAC, 2004, 76, 1033. (Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)) on page 1045 [Terms] [Paper]