The modification of an object which results in the loss of one or more symmetry elements, such as those which preclude @[email protected] (mirror plane, centre of @[email protected], rotation-reflection axis), as in the conversion of a @[email protected] molecular entity into a @[email protected] one.
PAC, 1996, 68, 2193. (Basic terminology of stereochemistry (IUPAC Recommendations 1996)) on page 2205 [Terms] [Paper]