feed-back inhibition (end product inhibition)

in biotechnology
https://doi.org/10.1351/goldbook.F02333
A metabolic control mechanism in which the end product of a biochemical @ST06775@ is able to inhibit the activity of an early @E02159@ in the @ST06775@, thereby controlling the metabolic flux through this pathway. As an example, isoleucine controls its own synthesis by inhibiting threonine deaminase; adenosine 5-triphosphate (ATP) and citrate control glycolysis by inhibiting phosphofructokinase.
Source:
PAC, 1992, 64, 143. (Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)) on page 154 [Terms] [Paper]
Cite as: IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997). Online version (2019-) created by S. J. Chalk. ISBN 0-9678550-9-8. https://doi.org/10.1351/goldbook.
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Last revised: February 24, 2014