intramolecular isotope effect

https://doi.org/10.1351/goldbook.I03132
A @[email protected] observed when a single substrate, in which the isotopic atoms occupy equivalent reactive positions, reacts to produce a non-statistical distribution of @[email protected] products. In such a case the @[email protected] will favour the pathway with lower @[email protected] for displacement of the isotopic nuclei in the @[email protected]
Source:
PAC, 1994, 66, 1077. (Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)) on page 1130 [Terms] [Paper]