For an @[email protected], there is often a particular activity of the measured ion for which the emf of the cell is independent of temperature. That activity, and the corresponding potential difference, defines the isopotential point. The specification of the @[email protected] and outer @[email protected] must be described. Comment: When an isothermal cell is used with identical reference electrodes, the isopotential point is the activity of sensed species that gives zero net @[email protected], e.g. sensed activity is the same in the inner and outer (test) solution. Calibration lines for different cell temperatures have different slopes, but intersect at a common activity point. Cells with temperature gradients are not recommended.