ligases (synthetases)

https://doi.org/10.1351/goldbook.L03521
@E02159@ that catalyse the ligation of two molecules with concomitant @H02902@ of the pyrophosphate bond in adenosine 5'-triphosphate (ATP) or a similar triphosphate, forming C–C, C–O, C–S, P–O or C–N bonds. In @D01579@, ligases covalently join together two sequences of @D01597@ (e.g. @H02859@ @D01597@ and foreign @D01597@) by a phosphodiester bond.
Source:
PAC, 1992, 64, 143. (Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)) on page 159 [Terms] [Paper]
Cite as: IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997). Online version (2019-) created by S. J. Chalk. ISBN 0-9678550-9-8. https://doi.org/10.1351/goldbook.
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Last revised: February 24, 2014