mechanism-based inhibition

Synonym: suicide inhibition
https://doi.org/10.1351/goldbook.M03805
Irreversible @[email protected] of an enzyme due to its @[email protected] of the reaction of an artificial substrate. Also called 'suicide inhibition'.
Source:
PAC, 1994, 66, 1077. (Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)) on page 1138 [Terms] [Paper]