https://doi.org/10.1351/goldbook.M04075
The frequency (\(\text{h}^{-1}\)) with which a @[email protected] occurs within a organism or @[email protected] In general, rates of spontaneous @[email protected] vary between one in \(10^{4}\) and one in \(10^{8}\) per gene per generation, and can be considerably increased by mutagens.