primary isotope effect
A @[email protected] attributable to isotopic substitution of an atom to which a bond is made or broken in the @[email protected] or in a @[email protected] step of a specified reaction. The corresponding @[email protected] on the @[email protected] of a reaction in which one or more bonds to isotopic atoms are broken, is called a 'primary @[email protected]'.
See also:
secondary isotope effect
PAC, 1994, 66, 1077. (Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)) on page 1130 [Terms] [Paper]